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Table 2 Odds ratios of sensitivity of thyroid hormone indices to risk of hyperuricemia by logistic regression analysis

From: Association of impaired sensitivity to thyroid hormones with hyperuricemia through obesity in the euthyroid population

 

Model 1

Model 2

OR (95% CI)

P value

OR (95% CI)

P value

TFQI

 Group 1 [−1, 0]

1 [Ref]

 

1 [Ref]

 

 Group 2 (0.000, 0.333]

1.048 (0.983–1.116)

0.152

1.019 (0.955–1.089)

0.566

 Group 3 (0.333, 0.667]

1.132 (1.049–1.222)

0.001

1.033 (0.955–1.118)

0.419

 Group 4 (0.667, 1.000]

1.403 (1.236, 1.594)

 < 0.001

1.183 (1.038–1.348)

0.012

PTFQI

 Group 1 [-1, 0]

1 [Ref]

 

1 [Ref]

 

 Group 2 (0.000, 0.333]

1.048 (0.983, 1.118)

0.148

1.023 (0.957–1.092)

0.507

 Group 3 (0.333, 0.667]

1.125 (1.043, 1.214)

0.002

1.025 (0.948–1.109)

0.528

 Group 4 (0.667, 1.000]

1.432 (1.264, 1.622)

 < 0.001

1.195 (1.051–1.359)

0.007

TT4RI

 Quartile 1 (~ , 21.733]

1 [Ref]

 

1 [Ref]

 

 Quartile 2 (21.733, 30.867]

0.973 (0.900–1.052)

0.498

1.003 (0.926–1.087)

0.935

 Quartile 3 (30.867, 42.693]

1.024 (0.948–1.107)

0.545

1.075 (0.992–1.164)

0.077

 Quartile 4 (42.693, ~]

1.084 (1.004–1.171)

0.039

1.169 (1.080–1.266)

 < 0.001

TSHI

 Quartile 1 (~ , 2.425]

1 [Ref]

 

1 [Ref]

 

 Quartile 2 (2.425, 2.814]

0.993 (0.918–1.074)

0.864

1.021 (0.942–1.107)

0.611

 Quartile 3 (2.814, 3.173]

1.049 (0.970–1.134)

0.230

1.071 (0.989–1.161)

0.092

 Quartile 4 (3.173, ~]

1.145 (1.060–1.237)

 < 0.001

1.120 (1.035–1.213)

0.005

  1. Model 1: crude model; model 2: adjusted for sex, age (continuous), education level (categorical), current smoking (categorical), current drinking (categorical), active physical activity (categorical), hypertension (categorical) and diabetes (categorical)
  2. OR odds ratio, CI confidence interval, TFQI thyroid feedback quantile-based index, PTFQI parametric thyroid feedback quantile-based index, TT4RI thyrotrophic thyroxine resistance index, TSHI thyroid-stimulating hormone index