Table 3 Interactive effects of group-by-time on EPS scores and prolactin levels (mean ± SD)
Baseline (n = 230) | Week 4 (n = 230) | Week 8 (n = 230) | Week 12 (n = 230) | Week 24 (n = 230) | Group (p value)a | Group × Time F (p value)a | |
|---|---|---|---|---|---|---|---|
ESRS total score | < 0.001 | 4.2 (0.028) | |||||
Control group | 12.2 ± 7.2 | 16.1 ± 8.1 | 20.8 ± 10.4 | 24.0 ± 12.1 | |||
RS group | 3.0 ± 1.7 | 5.9 ± 3.2 | 10.2 ± 4.7 | 15.1 ± 5.8 | |||
Benzhexol | < 0.001 | 9.1 (< 0.001) | |||||
Control group | 3.8 ± 1.3 | 4.5 ± 2.0 | 5.2 ± 2.2 | 5.5 ± 2.4 | |||
RS group | 1.4 ± 0.9 | 2.1 ± 1.3 | 2.9 ± 1.6 | 3.6 ± 1.9 | |||
Prolactin levels | < 0.001 | 18.9 (< 0.001) | |||||
Control group | 254.7 ± 55 | 846.3 ± 556 | 1272.0 ± 894 | 1728.6 ± 1289 | 2456.7 ± 1671 | ||
RS group | 259.1 ± 59 | 641.9 ± 310 | 939.2 ± 482 | 1244.7 ± 624 | 1688.1 ± 997 | ||