Fig. 2

Optical coherence tomography (OCT) examination and hematoxylin and eosin (HE) staining revealed retinal alterations in diabetic mice. A Representative OCT image. Ba The definition of the retinal layers in OCT images. Bb–Be The thickness of the total retina, inner layer, and middle retinal layer decreased in the T1D group compared with the control group but increased in the T1D + NaB group. The thickness of the outer retinal layers was not different among the three groups. C Representative retinal morphology images of HE staining. Da–Dd The thickness of the total retina, inner layer, and middle retinal layer decreased in the T1D group compared with the control group but increased in the T1D + NaB group. The thickness of the outer retinal layer was not different among the three groups. The data are presented as the mean ± SEM (n = 5). *p < 0.05, **p < 0.01, ***p < 0.001 compared with the control group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 compared with the T1D group. Scale bar: 100 μm for A, Scale bar: 20 μm for C