Fig. 3From: Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndromeEffects of sevoflurane on electrical resistance and proinflammatory cytokines levels in conditioned medium of mouse lung epithelial (MLE-12) cell monolayer. a Electrical resistance of a monolayer of MLE-12 cells was measured at a frequency at 4000 Hz by electric cell-substrate impedance sensing (ECIS) in untreated cells (Medium) or in cells treated for 24 h with cytomix alone (Cyto), sevoflurane alone (Sevo) or with cytomix and sevoflurane (Cyto + Sevo). Results are shown as medians with interquartile ranges (n = 35–40 per group and per timepoint). b Medium levels of Chemokine C-X-C motif ligand-1(CXCL-1), c Interleukin 6(IL-6) and d Tumor necrosis factor-alpha (TNF-α) at 6 h in identical conditions. Results are shown as medians with interquartile ranges (n = 3 per group). Two-way ANOVA test was performed, with post-hoc comparisons if ANOVA results showed significance (compared to the Medium group: *p < 0.05; **p < 0.01; ***p < 10–3; ****p < 10–4; compared to the Cyto group: ##p < 0.01; ###p < 10–3; ####p < 10–4)Back to article page