Fig. 7

Hierarchical clustering of expression of 10 genes in Parsortix harvests from HVs and MBC patients. The “labels” annotation across the top of the heatmap indicates results from HVs (blue) and MBC patients (red). The “PTPRC” annotation at the top of the heatmap and the scale of 1 to 8 to the right of the heatmap indicate logarithmic scaling of the level of PTPRC expression in the samples, which ranged from 278 to 11,300. The correlation coefficient (R) between the expression of individual genes and the WBC marker PTPRC is indicated in the annotations to the right of each gene name. Additionally, the ER, PR and HER2 assessments of the MBC patient’s tumors using results obtained from a review of their medical records are indicated at the top of the heatmap. Data were log2 transformed, and then the data for each probe in the columns were mean centered and scaled by dividing by the standard deviation for each probe. Colors represent relative Z-Scores. The distance method for hierarchical clustering was Euclidean, and the linkage method was Ward.D. The raw data are provided in Additional file 11.