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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Novel method for highly multiplexed gene expression profiling of circulating tumor cells (CTCs) captured from the blood of women with metastatic breast cancer

Fig. 6

Expression levels of KRT19 and EPCAM in Parsortix harvests from HVs and MBC patients. The log-transformed signal intensities of KRT19 and EPCAM are correlated to the log-transformed signal intensities of PTPRC for the HVs and the MBC patients (left side), and the expression levels are compared between the HV and MBC patients in combination boxplot/beeswarm plots (right side). The HVs are plotted in blue, and the MBC patients are plotted in red. The horizontal dotted line is drawn at an arbitrary cutoff of ten units. The green regression lines were fit only to samples with expression levels of KRT19 or EPCAM greater than the arbitrary threshold of ten units indicated by the horizontal dotted lines. The negative slopes of the PTPRC regression lines merely indicate that there was no meaningful correlation with PTPRC due to the small number of samples above the arbitrary threshold

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