The interplay between noncoding RNAs and drug resistance in hepatocellular carcinoma: the big impact of little things

Table 2 lncRNAs and drug resistance in HCC

lncRNA	Expression	Target	Drug	References
HCG18	Upregulated	GPX4	SOR	[173]
LINC01273	Upregulated	miR-600/METTL3	SOR	[174]
FAM225A	Upregulated	miR-130A-5p/CCNG1 axis	SOR	[127]
KCNQ1OT1	Upregulated	miR-506/PD-L1 axis	SOR	[129]
NIFK-AS1	Upregulated	OATP1B1 and OATP1B3	SOR	[130]
HANR	Upregulated	miR-29b/ATG9A axis	SOR	[175]
LIMT	Downregulated	miR-665	SOR	[176]
PURPL	Upregulated	P53	Doxorubicin	[177]
ARSR	Upregulated	Akt/NF-κB	Doxorubicin	[178]
PLAC2	Upregulated	miR-96	Cisplatin	[73]
LINC01234	Upregulated	miR-31-5p/MAGEA3 axis	Cisplatin	[132]
TPTEP1	Downregulated	IL-6/STAT3 axis	Cisplatin	[133]
LINC00173	Upregulated	miR-641/RAB14 axis	Cisplatin	[139]
TINCR	Upregulated	miR-195-3p/ST6GAL1 axis	OXA	[135]
LINC01134	Upregulated	SP1/p62	OXA	[137]
CCAT1	Upregulated	QKI-5/p38 MAPK	OXA	[179]
HOTAIR	Upregulated	miR-34a/AKT axis	paclitaxel	[138]
LINC00680	Upregulated	miR-153-3p/AKT3 axis	5-FU	[139]
SNHG16	Upregulated	miR-93	5-FU	[141, 142]
AY	Upregulated	ITGAV	5-FU	[141, 142]
SNHG3	Upregulated	miR-214-3p/ASF1B axis	ICI	[144]
AC099850.3	Upregulated	PRR11/PI3K/AKT axis	ICI	[146]
LINC00244	Downregulated	PD-L1	ICI	[147]
HOXA-AS3	Upregulated	miR-455-5p/PD-L1 axis	ICI	[148]
LINC00638	Upregulated	miR-4732-3p/ULBP1 axis	ICI	[148]
CASC11	Upregulated	EIF4A3/E2F1/PD-L1 axis	ICI	[150]
MT1JP	Upregulated	BCL2L2	Lenvatinib	[180]
Hsa_Circ_0006988	Upregulated	IGF1	SOR	[181]
CircKCNN2	Downregulated	miR-520c-3p/MBD2	Lenvatinib	[158]
CircRNA-001241	Upregulated	miR-21-5p	SOR	[182]
CircMRPS35	Upregulated	miR-148a/ STX3	Cisplatin	[183]
CircMEMO1	Downregulated	TCF21	SOR	[184]

ISSN: 1479-5876