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Table 1 Characteristics of the seven studies included in this meta-analysis

From: Comparison of serum acylcarnitine levels in patients with myalgic encephalomyelitis/chronic fatigue syndrome and healthy controls: a systematic review and meta-analysis

Study

Journal

Study design

Sample size, na

Sex female, n (%)

Age (SD or range)

ME/CFS/SEID patient group, n

Healthy control group, n

Kuratsune H, et al. [12]

Nihon rinsho

Retrospective study

59

34 (57.6)

35.9 (14–62)

27

41

Kuratsune H, et al. [13]

Clinical infectious diseases

Retrospective study

38

19 (50)

No data

38

308

Plioplys AV, et al. [14]

Neuropsychobiology

Retrospective study

35

27 (77.1)

40 (16–67)

M 8, F 27

M 40, F 45

Kuratsune H, et al. [15]b

International journal of molecular medicine

Retrospective study

57

57 (100)

No data

57

46

Kuratsune H, et al. [15]c

International journal of molecular medicine

Retrospective study

146

82 (56.2)

No data

M 64, F 82

M 177, F 131

Soetekouw PM, et al. [16]

The Netherlands journal of medicine

Retrospective study

25

25 (100)

35.9 (9.8)

25

25

Jones MG, et al. [17]

Clinica chimica acta

Retrospective study

31

19 (61.3)

M 42 (26–63), F 42 (21–84)

31

31

Reuter SE, et al. [18] 

Journal of internal medicine

Retrospective study

44

27 (61.4)

49.9 (15)

44

49

  1. aThe number of patients diagnosed with ME/CFS/SEID according to the diagnostic criteria [3, 19,20,21]
  2. bCharacteristics of Swedish patients with ME/CFS/SEID [15]
  3. cCharacteristics of Japanese patients with ME/CFS/SEID [15]
  4. ME myalgic encephalomyelitis, CFS chronic fatigue syndrome, SEID systemic exertion intolerance disease, n number, SD standard deviation, M male, F female