Fig. 5

Motif transcriptional regulation analysis. a The three motifs with the highest AUC values. The red line is the average of the recovery curve of each motif, the green line is the mean + standard deviation, and the blue line is the recovery curve of the current motif. The maximum distance point (mean + sd) between the current motif and the green curve is the maximum enrichment level selected. b Demonstration of the highest motif enrichment of AUC, including NES (standardized enrichment score for motifs in gene sets), AUC (area under the curve), and TF_highConf (transcription factors annotated to motifs). c miRNA networks of hub genes, pink for mRNA and purple for miRNA