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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Suicide gene therapy using allogeneic adipose tissue-derived mesenchymal stem cell gene delivery vehicles in recurrent glioblastoma multiforme: a first-in-human, dose-escalation, phase I clinical trial

Fig. 3

The high efficiency transduced U-251/PCDH (transfected with the plasmid without the HSV-TK gene) and U-251/HSV-TK cells (more than 80% of population) observed using fluorescent microscopy (A). The viability of U-251 in serial dilution rate of ganciclovir (GCV) concentration was determined with MTT assay (* p < 0.05) (B). The relative cell survival rates of U-251/TK and U-251/PCDH cells treated in a range of GCV concentration for 96 h (* P  < 0.05) (C). U-251/PCDH (D) and U-251/HSV-TK (E) in 0 µg/mL (A), 5 µg/mL (B), 10 µg/mL (C), and 20 µg/mL (D) of GCV

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Journal of Translational Medicine

ISSN: 1479-5876

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