Fig. 4
From: Intraparenchymal convection enhanced delivery of AAV in sheep to treat Mucopolysaccharidosis IIIC
Comparative distribution of GFP expression in sheep brains in study 2. Images showing GFP expression in sheep brains 3 weeks post-injection. Two groups received either A AAV9-GFP (n=3) or B AAV-TT GFP (n=2) into the corpus striatum (CS) only. C An additional group of sheep (n=2) received AAV-TT-GFP into the CS, white matter (WM) and brainstem (BS). D Average GFP expression across each sagittal brain level. E Average GFP expression across the entire hemisphere. Data are presented as mean ± s.e.m