Fig. 3

Association of handgrip strength, vitamin D, and APOE e4 genotype with incident dementia risk in women and men. A1 Joint effect of handgrip strength and APOE e4 genotype on dementia in women; A2 Joint effect of vitamin D and APOE e4 genotype on dementia in women; A3 Joint effect of handgrip strength, vitamin D, and APOE e4 genotype on dementia in women; B1 Joint effect of handgrip strength and APOE e4 genotype on dementia in men; B2 Joint effect of vitamin D and APOE e4 genotype on dementia in men; B3 Joint effect of handgrip strength, vitamin D, and APOE e4 genotype on dementia in men. Cox regression model is adjusted for age, ethnicity, education level, socioeconomic status, alcohol consumption, smoking status, BMI, heart disease, stroke, hypertension, diabetes, depression, TC, HDL, LDL, and we adjusted for vitamin D in handgrip strength analysis or for handgrip strength in vitamin D analysis