Fig. 5

Circ0001955 promotes SiHa cell proliferation and invasion and activates AKT-mTOR pathway through the circ0001955/miR-188-3p/NCAPG2 axis A The proliferative abilities of SiHa cells were detected by Edu assays in the indicated cells. Original magnification, × 100. Scale bar, 750 μm. B and C Transwell assays were performed to investigate the migration and invasion abilities of SiHa cells in the indicated groups. Original magnification, × 100. Scale bar, 200 μm. D Apoptotic cells were assessed by TUNEL after transfected with indicated plasmids. Scale bar, 1000 μm. E and F The cell cycle progression was analyzed by flow cytometry after being transfected with indicated plasmids. *P < 0.05, **P < 0.01, ***P < 0.001.