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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: HNRNPA2B1-mediated m6A modification of lncRNA MEG3 facilitates tumorigenesis and metastasis of non-small cell lung cancer by regulating miR-21-5p/PTEN axis

Fig. 5

HNRNPA2B1 mediated lncRNA MEG3 to regulate miR-21-5p/PTEN axis in NSCLC cells. A The luciferase activity of the WT luc-PTEN or Mut luc-PTEN after transfection with miR-21-5p mimics in 95D and H1299 cells. B RT-qPCR analysis of the effects of co-transfection with miR-21-5p inhibitor and (or) si-MEG3 on PTEN expression in 95D and H1299 cells. C Western blot analysis of the effects of co-transfection with miR-21-5p inhibitor and (or) si-MEG3 on PTEN/PI3K/AKT signaling activity in 95D and H1299 cells. D Western blot analysis of the effects of co-transfection with sh-HNRNPA2B1 and (or) si-MEG3 on PTEN/PI3K/AKT signaling activity in 95D and H1299 cells

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Journal of Translational Medicine

ISSN: 1479-5876

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