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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: HNRNPA2B1-mediated m6A modification of lncRNA MEG3 facilitates tumorigenesis and metastasis of non-small cell lung cancer by regulating miR-21-5p/PTEN axis

Fig. 2

Knockdown of HNRNPA2B1 repressed growth and invasion of NSCLC cells. A RT-qPCR analysis of the mRNA expression levels of HNRNPA2B1 in BEAS-2B and NSCLC cell lines. B RT-qPCR and Western blot analysis of the transfection efficiency of sh-HNRNPA2B1 in 95D and H1299 cells or HNRNPA2B1 in A549 and PC9 cells. C MTT analysis of the effects of HNRNPA2B1 knockdown or overexpression on the cell viability of NSCLC cells. D Colony formation analysis of the effects of HNRNPA2B1 knockdown or overexpression on the colony formation ability of NSCLC cells. E Transwell analysis of the effects of HNRNPA2B1 knockdown or overexpression on the cell invasion of NSCLC cells. Data are the means ± SEM of three experiments. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

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