Fig. 6
The Regulations of TFAP2 on ferroptosis process Ferroptosis is characterized by abnormal iron metabolism and accumulation, lipid biosynthesis and peroxidation, and ROS (reactive oxygen species) in cell, and eventually regulates the process of cell death. TFAP2 members multidimensionally involve ferroptosis process by directly regulating ferroptosis-related proteins.Only validated direct protein–protein interaction and DNA/RNA–protein interaction are shown. (Created with BioRender.com)