Fig. 3

The basic information of the 16S rRNA gene sequencing. The species accumulation curve of gut microbiota detected in HTN and control subjects in this study (A). The line indicates the averaged accumulated increase of detected OTUs vs. number of samples. The box-plots show the 25th, 50th and 75th percentile at each sample size. The rarefaction curve of the number of sequence reads and their corresponding number of OTUs in females and males in this study (B). Venn diagrams of observed OTU numbers in different comparison groups: females vs. males (C), HTN group vs. control group in females (D) and males (E), respectively. Every circle depicts the number of unique OTUs observed in one group. Overlapping OTUs shared by two groups are represented in the areas of intersection among corresponding circles