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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages

Fig. 5

scRNA-seq revealed the localization of core m6A regulators and their targeting genes. A t-SNE plot of cells belonging to 3 OA synovium samples, showing six transcriptionally distinct cell clusters. B Dot plot of representative marker genes of six synovial cell clusters. C Heatmap of six core m6A regulator expressions in synovial cell clusters. D Feature plots of AUCell scores of core m6A regulators upregulated genes in each cell cluster. Redder dots represent cells with higher AUCell scores. E Feature plots of AUCell scores of core m6A regulators downregulated genes in each cell cluster. Redder dots represent cells with higher AUCell scores

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