Fig. 2

The ordered-scores map displays performance of the model for ICI response trained without SD patient samples. Top panel shows predictions from the peptides derived from the iterated 80% resampling analysis; lower panel displays independent model testing on serum samples from SD patients. Both observed and predicted responder samples and responder associated FSPs are shown in green; observed and predicted non-responder samples and non-responder associated FSPs are shown in red. Observed stable disease samples are shown in tan. Axes labels and other abbreviations are defined in Fig. 1. R-FSP, responder associated FSPs; NR-FSPs, non-responder FSPs