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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Screening of immune-related secretory proteins linking chronic kidney disease with calcific aortic valve disease based on comprehensive bioinformatics analysis and machine learning

Fig. 4

Identification of CKD-associated secretory proteins through differential expression analysis on secretory proteins in PMBC and kidney tissues of CKD. A The volcano plot revealing DEGs in the CKD-PMBC dataset. B The heatmap representing the top 30 upregulated and 30 downregulated DEGs in the CKD-PBMC dataset. C The volcano plot displaying DEGs in the CKD-Kidney dataset. D The heatmap displaying the top 30 upregulated and 30 downregulated DEGs in the CKD-Kidney dataset. E The intersection of CKD-PMBC DEGs with genes coding secretory proteins via the venn diagram. F The intersection of CKD-Kidney DEGs with genes coding secretory proteins via the venn diagram, and altogether 983 CKD-associated secretory proteins were identified. CKD chronic kidney disease, PBMC peripheral blood mononuclear cells, DEG differentially expressed genes

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Journal of Translational Medicine

ISSN: 1479-5876

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