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Table 3 Sensitivity analysis: adjusted hazard ratios and 95% confidence intervals for future risk of diabetes associated with baseline TyG index and TyG-related parameters in different test populations

From: Assessing temporal differences in the predictive power of baseline TyG-related parameters for future diabetes: an analysis using time-dependent receiver operating characteristics

 

HR (95% CI)

Sensitivity-1

Sensitivity-2

Sensitivity-3

Sensitivity-4

TyG index (per SD increase)

1.30 (1.11, 1.52)

1.34 (1.13, 1.59)

1.36 (1.08, 1.73)

1.42 (1.15, 1.75)

TyG-BMI (per SD increase)

1.47 (1.29, 1.68)

1.58 (1.37, 1.81)

1.37 (1.08, 1.74)

1.33 (1.00, 1.78)

TyG-WC (per SD increase)

1.65 (1.42, 1.92)

1.78 (1.52, 2.09)

1.39 (1.07, 1.81)

1.61 (1.23, 2.11)

TyG-WHtR (per SD increase)

1.59 (1.39, 1.83)

1.71 (1.48, 1.98)

1.37 (1.08, 1.74)

1.56 (1.22, 2.00)

  1. HR hazard ratios, CI confidence interval, other abbreviations as in Table ​1;
  2. (1) Sensitivity-1: Further adjustment of liver enzyme-related variables (n = 15,464)
  3. (2) Sensitivity-2: Participants with a follow-up of less than 2 years were excluded (n = 12,823)
  4. (3) sensitivity-3: Participants diagnosed with the fatty liver at baseline were excluded (n = 12,723)
  5. (4) sensitivity-4: Participants with BMI ≥ 25 kg/m2 at baseline were excluded (n = 12,940);
  6. Sensitivity-1 adjusted for sex, age, height, TC, HDL-C, HbA1c, SBP, Fatty liver, exercise habits, drinking status, smoking status, ALT, AST, and GGT
  7. Sensitivity-2 adjusted for sex, age, height, TC, HDL-C, HbA1c, SBP, Fatty liver, exercise habits, drinking status, and smoking status. Sensitivity-3 adjusted for sex, age, height, TC, HDL-C, HbA1c, SBP, exercise habits, drinking status, and smoking status
  8. Sensitivity-4 adjusted for sex, age, height, TC, HDL-C, HbA1c, SBP, Fatty liver, exercise habits, drinking status, and smoking status
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Journal of Translational Medicine

ISSN: 1479-5876

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