Skip to main content

Table 1 Participant demographics and clinical information

From: Detection of mild cognitive impairment in Parkinson’s disease using gradient boosting decision tree models based on multilevel DTI indices

 

PD-MCI (n = 68)

PD-NC (n = 52)

P value

Age (years)

64.43 ± 7.86

62.73 ± 7.79

0.242a

Gender (male/female)

36/32

28/24

0.922b

Education (years)

9.0 (7.3–12.0)

9.0 (9.0–12.0)

0.111c

Disease duration (years)

4.5 (2.0–7.0)

3 (2.0–6.0)

0.510c

MDS-UPDRS-IIII

25.55 ± 10.84

23.54 ± 13.47

0.366a

H&Y stage

2.0 (1.5–3.0)

2.0 (1.5–2.5)

0.337c

LEDD (mg)

363.97 ± 73.10

356.02 ± 108.17

0.632a

MMSE

25.17 ± 2.20

28.47 ± 1.33

< 0.001a**

MoCA

21.65 ± 2.78

26.71 ± 1.59

< 0.001a*

CDT

6.5(5.0–9.0)

8.0 (7.0–10.0)

< 0.001c**

AVLT

30.31 ± 4.44

40.48 ± 3.23

< 0.001a**

TMT-A

74.49 ± 18.36

67.65 ± 18.30

0.045a**

TMT-B

221.18 ± 59.78

167.14 ± 60.17

< 0.001a**

HAMD

13.08 ± 6.81

11.85 ± 6.41

0.317a

  1. Data are represented as the mean ± SD or median (p25-p75) values depending on the distribution of the variables. a Two sample t test; b Chi-square test; c Mann‒Whitney U test; *P < 0.05. PD-MCI Parkinson’s disease with mild cognitive impairment, PD-NC Parkinson’s disease with normal cognition, MDS-UPDRS-IIII Movement Disorder Society Unified Parkinson’s Disease Rating Scale-Part III, H&Y stage Hoehn and Yahr stage, LEDD levodopa equivalent daily dose, MMSE Minimum Mental State Examination, MoCA Montreal Cognitive Assessment, CDT Clock Drawing Test, AVLT Auditory Verbal Learning Test, TMT-A, TMT-B Trail Making Test A and B, HAMD Hamilton Depression Scale
Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us