Fig. 2

Plasma cell infiltration levels inferred from bulk RNA-seq data correlate with survival and immunotherapy response. A Association between inferred B-cell subtype infiltration levels and patient overall survival in the TCGA-BLCA cohort (Cox regression analysis). B Kaplan–Meier curves for TCGA-BLCA patients. The P value was calculated with the log-rank test. C Association between inferred B-cell subtype infiltration levels and patient overall survival in the anti-PD-L1 IMvigor210 cohort (Cox regression analysis). D Kaplan–Meier curves for IMvigor210 patients. The P value was calculated with the log-rank test. E Box and violin composite plots showing a higher plasma cell infiltration level in the response (R) group than in the nonresponse (NR) group. Wilcoxon test; *P < 0.05