Fig. 2

Application scenarios of spatial transcriptomics. “Tissue Architecture” refers to studies that elucidate the spatial distribution of cell subpopulations in a specific tissue and decode intercellular interaction. “Tissue Development” represents research into resolving morphogenesis patterns and spatiotemporal gene expression of the transcriptome during the development course of a certain tissue or organ. “Disease Research” demonstrates disease microenvironment and pathogenesis, and among the disease research, tumor biology is an important part including tumor microenvironment and heterogeneity