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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function

Fig. 4

Increased expression of EP/p300 may repurpose TNF actions in Long-COVID. A Diagram shows TGFβ signaling pathways. Up-regulated biomarkers are shown in red and down-regulated in blue (KEGG Mapper, confirmed by iPathwayGuide software). B Graphs represent the expression levels of markers associated with the TGFβ1 pathway. Statistical significance was established using GraphPad-9, and P-value was considered significant if < 0.05 with Mann–Whitney U test. Key protein interactions are presented in the diagram from the middle panel (right side), an output of STRING confirmed with iPathwayGuide software. Fluctuation of the TGFβ and TNFα may impact EP/p300 epigenetic activity

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Journal of Translational Medicine

ISSN: 1479-5876

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