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Table 4 Association of miR-146a rs2910164 polymorphisms with MACE

From: MiR-146a rs2910164 (G/C) polymorphism is associated with the development and prognosis of acute coronary syndromes: an observational study including case control and validation cohort

 

Patients without MACE

Patients with MACE

HR(95%CI)

P value

 

(n = 440)

(n = 172)

miR146aC > G

    

CC

160 (36.36%)

47 (27.33%)

1.000 (reference)

 

CG

213 (48.41%)

89 (51.74%)

1.146 (0.966–1.359)

0.118

GG

67 (15.23%)

36 (20.93%)

1.732 (1.123–2.671)

0.013

Dominant model (CC vs. CG + GG)

 

1.405 (1.018–1.939)

0.038

Recessive model (CC + CG vs. GG)

 

1.107 (0.821–1.492)

0.506

HWE χ2

0.080

0.263

  

HWE p

0.778

0.608

  
  1. miRNA microRNA; MACE major adverse cardiovascular events; HR Hazard ratio; HWE Hardy–Weinberg equilibrium, CI Confidence interval