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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Preventative effect of TSPO ligands on mixed antibody-mediated rejection through a Mitochondria-mediated metabolic disorder

Fig. 7

TSPO ligands inhibit mitochondrial respiration and glycolysis in B cells in vitro. A The oxygen consumption rate (OCR) of human B cells 48 h after treatment with FGIN1-27 or Ro5-4864. B Bar graph of basal and maximal (Max.) respiration of B cells 48 h after treatment with FGIN1-27 or Ro5-4864. C The extracellular acidification rate (ECAR) of human B cells 48 h after treatment with FGIN1-27 or Ro5-4864. D Bar graph of glycolysis and glycolytic (Glyco.) capacity of B cells 48 h after treatment with FGIN1-27 or Ro5-4864. n = 5; *P < 0.05; **P < 0.01

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