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Table 6 Virological and immunological parameters according to immunocompromised vs non-immunocompromised status

From: Taxonomic reclassification of Kaposi Sarcoma identifies disease entities with distinct immunopathogenesis

Ā 

Immunosuppressed

Non-immunosuppressed

Total

Ā 

Total

593

83

676

Ā 

HHV8

Ā Ā Ā Ā 

Ā Data available for

451

72

523

Ā 

Ā Blood HHV8 detectable

224/451

(49%)

27/72 (37%)

251/523

(48%)

Ā 

Ā Mean HHV8 viral load

Range (copies/ml)

1.7Ā M

0ā€“554M

2.9K

0ā€“83K

1.4M

0ā€“554M

MW Pā€‰=ā€‰0.007

Ā Mean log HHV8 Viral load (range)

4.2(1.6ā€“8.7)

3.3 (2.2ā€“4.9)

4.0 (1.6ā€“8.7)

MW Pā€‰=ā€‰0.010

Leukocytes (cells/Āµl)

Ā Ā Ā Ā 

Ā Data available for

564

72

636

Ā 

Ā Mean count (range)

5.6 (1.2ā€“24)

6.4 (2.9ā€“13)

5.7 (1.2ā€“24)

MW Pā€‰=ā€‰ā€‰<ā€‰0.001*

Lymphocytes (cells/Āµl)

Ā Ā Ā Ā 

Ā Data available for

561

72

633

Ā 

Ā Mean count (range)

1.7(0.1ā€“6.1)

1.7 (0.6ā€“3.0)

1.7 (0.1ā€“6.1)

MW Pā€‰=ā€‰0.378

CD4 cells/Āµl

Ā Ā Ā Ā 

Ā Data available for

507

69

576

Ā 

Ā Mean count (range)

268 (0ā€“1899)

769 (74ā€“1779)

317(0ā€“1850)

MW Pā€‰<ā€‰0.001*

CD4 cell %

Ā Ā Ā Ā 

Ā Data available for

533

69

591

Ā 

Ā Mean count (range)

17% (0ā€“55)

45% (11ā€“79)

20% (0ā€“79)

MW Pā€‰<ā€‰0.001*

CD8 cells/Āµl

Ā Ā Ā Ā 

Ā Data available for

520

69

578

MW Pā€‰<ā€‰0.001*

Ā Mean count (range)

894 (0ā€“9090)

448 (65ā€“1117)

839(0ā€“9090)

Ā 

CD8 cell %

Ā Ā Ā Ā 

Ā Data available for

518

69

576

MW Pā€‰<ā€‰0.001*

Ā Mean count (range)

58% (0ā€“90)

26% (10ā€“59)

54% (0ā€“90)

Ā