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Table 2 Clinicopathological features of patients with KS

From: Taxonomic reclassification of Kaposi Sarcoma identifies disease entities with distinct immunopathogenesis

Ā 

HIV associated KS

Classic KS

Endemic KS

Iatrogenic KS

MSM KS

Total

Total

572

23

19

21

41

676

Gender

Ā Ā Ā Ā Ā Ā 

Ā Cis-male

531 (93%)

18 (78%)

14 (74%)

18 (86%)

41 (100%)

622 (92%)

Ā Cis-female

39 (7%)

5 (22%)

5 (26%)

3 (14%)

0 (0%)

52 (7%)

Ā Trans-female

2 (0.3%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

2 (1%)

Mean Age (years)

Range

41

16ā€“75

74

39ā€“88

59

15ā€“78

55

22ā€“73

52

31ā€“84

43

16ā€“88

Race

Ā Ā Ā Ā Ā Ā 

Ā White-Caucasian

43 (76%)

8 (35%)

1 (5%)

6 (28%)

35 (85%)

48 (72%)

Ā Black-African

10 (18%)

7 (30%)

13 (68%)

10 (48%)

3 (7%)

135 (20%)

Ā Asian

32 (6%)

0 (0%)

2 (11%)

0 (0%)

2 (5%)

36 (5%)

Ā Other

3 (0.5%)

8 (35%)

3 (16%)

5 (24%)

1 (2%)

20 (3%)

Skin sites of KS lesions

Ā Localised

149 (26%)

16 (69%)

10 (53%)

8 (38%)

25 (61%)

208 (31%)

Ā Regional

73 (13%)

4 (17%)

0 (0%)

3 (14%)

1 (2%)

81 (12%)

Ā Disseminated

324 (57%)

2 (9%)

9 (47%)

8 (38%)

13 (32%)

357 (53%)

Ā None

26 (4%)

0 (0%)

0 (0%)

2 (9%)

2 (5%)

30 (4%)

Histological grades of KS

Ā Ā Ā Ā Ā Ā 

Ā Patch

91 (16%)

0 (0%)

0 (0%)

2 (10%)

3 (7%)

96 (14%)

Ā Plaque

266 (47%)

7 (30%)

2 (11%)

3 (14%)

15 (37%)

293 (43%)

Ā Nodular

169 (30%)

12 (51%)

16 (84%)

14 (67%)

20 (49%)

231 (34%)

Ā Not otherwise specified

46 (8%)

4 (17%)

1 (5%)

2 (10%)

3 (7%)

56 (8%)

Disease Extent

Ā Ā Ā Ā Ā Ā 

Ā Disease limited to Skin

429 (75%)

21 (91%)

15 (79%)

11 (52%)

39 (95%)

515 (161%)

Ā Advanced KS any site*

143 (25%)

2 (9%)

4 (21%)

10 (48%)

2 (5%)

161 (24%)

Sites of advanced KS involvement at diagnosis*

Ā Ā 

Ā Gastro-intestinal

50 (9%)

1 (4%)

2 (11%)

3 (14%)

0 (0%)

56 (8%)

Ā Pulmonary

60 (10%)

2 (9%)

2 (11%)

6 (28%)

0 (0%)

70 (10%)

Ā Other Viscera

94 (16%)

2 (9%)

4 (21%)

8 (38%)

2 (5%)

110 (16%)

Ā Extensive oral involvement

81 (14%)

0 (0%)

0 (0%)

3 (14%)

0 (0%)

84 (12%)

Characteristics of advanced KS at diagnosis

Ā Ā Ā Ā 

Ā Tumour Associated Odema

87 (15%)

6 (26%)

8 (42%)

6 (28%)

3 (7%)

110 (16%)

Ā Tumour Ulceration

60 (10%)

4 (17%)

4 (21%)

4 (19%)

3 (7%)

75 (11%)

  1. *Sites of advanced disease defined as visceral (GI, Pulmonary, other visceral) plus extensive oral involvement