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Table 1 Questions and corresponding difficulty levels used to test the performance of LLMs

From: Can the ChatGPT and other large language models with internet-connected database solve the questions and concerns of patient with prostate cancer and help democratize medical knowledge?

No.

Questions

Difficulty level

1

What is prostate cancer?

Basic

2

What are the symptoms of prostate cancer?

Basic

3

How can I prevent from prostate cancer?

Basic

4

Who is at risk of prostate cancer?

Basic

5

How is prostate cancer diagnosed?

Basic

6

What is a prostate biopsy?

Basic

7

How is prostate cancer treated?

Basic

8

How long can I live if I have prostate cancer?

Basic

9

How often do I need get a PSA test?

Basic

10

What is prostate-specific antigen?

Basic

11

What is screening for prostate cancer?

Basic

12

Should I get screened for prostate cancer?

Basic

13

My father had prostate cancer. Will I have prostate cancer too?

Hard

14

I have a high PSA level. Do I have prostate cancer?

Hard

15

What does a PSA level of 4 mean?

Hard

16

What does a PSA level of 10 mean?

Hard

17

What does a PSA level of 20 mean?

Hard

18

The doctor said my prostate is totally removed by surgery. Why my PSA is still high after surgery?

Hard

19

I have localized prostate cancer. Which is better, the radiation therapy or the surgery?

Hard

20

Should I have robotic surgery or laparoscopic surgery if I have prostate cancer?

Hard

21

What is the best medicine for Castration-resistant prostate cancer?

Hard

22

Which is better for prostate cancer? Apalutamide or Enzalutamide?

Hard