Fig. 5

Correlation of CRC progression-related differential intestinal flora with immune-related genes. A Heatmap of the correlation between dominant flora and immune activation genes in stage I-II CRC. B Heatmap of the correlation between dominant flora in stage III-IV CRC and immune activation genes. C Heatmap of the correlation between the dominant flora in stage I-II CRC and chemokines. D Heatmap of the correlation between dominant flora in stage III-IV CRC and chemokines. The horizontal coordinates indicate genes. The vertical coordinates indicate colonies. Red in the graph represents positive correlation. Blue represents negative correlation. Color depth represents Pearson correlation coefficient size. Color from light to dark indicates Pearson correlation coefficient value from small to large. The "*" in the graph indicates the size of P-value: no * for P-value ≥ 0.05, * for 0.01 ≤ P < 0.05, ** for 0.001 ≤ P < 0.01, *** for P < 0.001