Fig. 4

STIL depletion inhibits tumour growth in vivo. A Bioluminescent images of xenograft bladder-tumor mouse models implanted with STIL depletion cells. B The volume of bladder tumour in 1–4 weeks. C, D Photograph of xenograft subcutaneous bladder tumours (left). Statistical analysis of the tumour weights (right). E The western blot analysis of xenograft subcutaneous bladder tumours' protein expression (STIL, GLI1, SHH, Acetylated tubulin, IFT88, and SMO). The percentage of protein levels was quantification. Unpaired t-test analysis was utilized to compare the differences between the two groups. *P-value < 0.05, **P-value < 0.01, ***P-value < 0.001, ****P-value < 0.0001