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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Phospholipase A2 regulates autophagy in gouty arthritis: proteomic and metabolomic studies

Fig. 6

Interactions between the proteome and metabolome, and validation of the autophagy pathway. A: Example diagram of protein and metabolism KGML network. Squares represent pathways, triangles represent proteins, and circles represent metabolites. Red indicates up-regulated proteins or green indicates down-regulated proteins or metabolites. B: The expressions of LC3B and SQSTM1/62 were evaluated by western blotting. C: The expressions of PLA2 were evaluated by western blotting. D-F: Quantification of LC3B, SQSTM1/62 and PLA2 expressions (n = 3, all the data are expressed as means ± SD, two-way ANOVA followed by Turkey's post hoc test was applied). * means P < 0.05, ** means P < 0.01, *** means P < 0.001

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