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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2

Fig. 4

ILA alleviated intestinal inflammation and promoted intestinal regeneration by promoting YAP expression. A Gene expression levels of TNF-α, IL-6 and IL-1β in intestinal tissue (n = 4–7/group). B Cytokines TNF-α and IL-6 levels in serum (n = 4–7/group). C Relative LDH levels in the serum (n = 4–7/group). D-F Immunofluorescence of Ki67 (D), lysozyme (E) and Muc2 (F) in intestinal tissue sections. Results are presented as mean ± SEM. The statistical tests employed included: one-way ANOVA followed by the Tukey test for multiple comparisons in A–C. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001

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