Molecular fingerprints of nuclear genome and mitochondrial genome for early diagnosis of lung adenocarcinoma

Table 6 Somatic mutations of nuclear genome in the plasma cfDNA of the training data set for the diagnosis of early-stage LUAD

TT: the selected genes whose mutations was associated with higher TMB in tumor tissues; CFT: the selected genes whose mutations was associated with higher TMB in cfDNA of LUAD patients; HC: the selected genes whose variation frequencies in tumor tissues and cfDNA were both > 25%; THF: the top five mutation genes in tumor tissues; CFHF: the top five mutation genes in cfDNA of LUAD patients; ALL: all the selected genes above

ISSN: 1479-5876