Fig. 2

The genetic changes and pathway aberrations enriched after LM. A The genetic profile of the pre-LM primary tumor tissue and the matched post-LM CSF samples. B The genetic alterations and signaling pathway aberrations that were enriched in post-LM CSF samples when compared with pre-LM primary tumor tissues. C The frequency of MYC and CCNE1 amplification among primary tumors in our cohort, primary tumors in the TCGA cohort, and the CSF samples in our cohort