Table 3 Results from Multivariate Cox Proportional Hazard Models for DFS and OS
From: Analysis of clinical features, genomic landscapes and survival outcomes in HER2-low breast cancer
Parameter | HR (95% CI) | P value | |
|---|---|---|---|
DFS | |||
Ki67% | 2.08 (1.53–2.82) | < 0.001 | |
T stage | ≤ T1 vs > T1 | 1.15 (0.90–1.47) | 0.269 |
N stage | N− vs N+ | 1.38 (1.07–1.77) | 0.012 |
HR statusa | HR− vs HR+ | 0.51 (0.39–0.67) | < 0.001 |
HER2 statusa | HER2-low vs HER2-zero | 1.15 (0.86–1.54) | 0.344 |
HER2-low vs HER2+ | 1.00 (0.72–1.39) | 0.997 | |
OS | |||
Age | 1.02 (1.01–1.03) | 0.003 | |
Ki67% | 1.01 (1.002–1.014) | 0.007 | |
HR statusa | HR− vs HR+ | 0.46 (0.35–0.62) | < 0.001 |
HER2 statusa | HER2-low vs HER2-zero | 1.40 (1.06–1.86) | 0.017 |
HER2-low vs HER2+ | 0.36 (0.26–0.51) | < 0.001 | |
Initial metastasis sites | With visceral organ vs without | 1.59 (1.13–2.23) | 0.007 |
With lung vs without | 0.94 (0.69–1.28) | 0.678 | |