Fig. 5

Correlation between mRNA expression of transcription factor genes in renal tubulointerstitium and GFR in DN patients. a–o The mRNA expression of AP1 (p = 0.009, r = − 0.740; p = 0.010, r = − 0.735), CDC5(from ERCB: p = 0.006, r = − 0.862; from Woroniecka: p = 0.031, r = − 0.678), IRF1 (p = 0.002, r = − 0.816; p = 0.046, r = − 0.611 ), POU3F2 (p = 0.046, r = − 0.640), SOX9 (p = 0.009, r = − 0.743), BACH1 (p = 0.013, r = − 0.819), SOX5 (p = 0.001, r = − 0.920; p = 0.044, r = − 0.823), FAC1 (p = 0.023, r = − 0.777), TGIF1 (p = 0.010, r = − 0.836; p = 0.047, r = − 0.609), FOXJ2 (p = 0.011, r = − 0.731) negatively correlated with GFR. p, q The mRNA expression of FOXO1 (p = 0.027, r = 0.691), FOXO4 (p = 0.007, r = 0.561) positively correlated with GFR. p < 0.05 was considered statistically significant. GFR: glomerular filtration rate; MDRD: modification of diet in renal disease; CG: Cockcroft Gault