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Table 1 Patient characteristics

From: Klebsiella quasipneumoniae in intestine damages bile acid metabolism in hematopoietic stem cell transplantation patients with bloodstream infection

 

BSI (n = 21)

non-BSI (n = 16)

P valued

Age at diagnosis (year)a

39.8 ± 15.8

41.6 ± 18.9

0.746

Gender (M/F)

M 15

F 6

M 10

F 6

0.726

Primary disease

–

 AML

10

2

 ALL

2

3

 CMML

–

1

 MDS

2

2

 Lymphoma

4

–

 MM

1

6

 AA

1

1

 POEMS syndrome

1

–

 PNH

–

1

Types of HSCT

allo-HSCT 19

auto-HSCT 2

allo-HSCT 10

auto-HSCT 6

0.055

Liver function

 ALT (U/L)a

70.4, 78.4

19.3, 11.5

0.001

 AST (U/L)a

40.9, 38.7

19.0, 9.8

0.057

 GGT (U/L)a

144.4, 151.9

42.1, 40.8

< 0.001

Total bilirubin (µmol/L)a

22.2, 28.6

12.2, 5.2

0.058

Direct bilirubin (µmol/L)a

13.24, 22.8

4.8, 2.3

0.003

BSI related pathogensb

–

Coagulase-Negative Staphylococcusc

4

–

Enterococcus faecium

1

–

Streptococcus spp.

2

–

Enterobacter cloacae

2

–

Escherichia coli

5

–

Klebsiella pneumoniae

1

–

Pseudomonas aeruginosa

6

–

Corynebacterium jeikeium

1

–

  1. a Mean ± SD; b One patient had a mixed Staphylococcus epidermidis and Streptococcus oral infection; c Eliminate possible contamination according to BSI diagnostic criteria; d Students' t-test was used for data with a homogeneous variance; otherwise, Mann–Whitney U test was used; Fisher's exact test was used for counts
  2. AML: acute myeloid leukaemia; ALL: acute lymphoblastic leukaemia; CMML: chronic myelomonocytic leukemia; MDS: myelodysplastic syndromes; MM: multiple myeloma; AA: aplastic anemia; PNH: paroxysmal nocturnal hemoglobinuria