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Table 1 clinicopathologic features in 12 patients with GIST

From: Mesenchymal stromal cells promote the drug resistance of gastrointestinal stromal tumors by activating the PI3K-AKT pathway via TGF-β2

Characteristic

Primary lesions

Post-drug resistance

p

n

9

9

 

T stage, n (%)

  

0.813

 T1

2 (11.1%)

2 (11.1%)

 

 T2

4 (22.2%)

6 (33.3%)

 

 T3

2 (11.1%)

1 (5.6%)

 

 T4

1 (5.6%)

0 (0%)

 

M stage, n (%)

  

0.082

 M0

9 (50%)

5 (27.8%)

 

 M1

0 (0%)

4 (22.2%)

 

Pathology, n (%)

  

0.058

 Ib

0 (0%)

1 (5.6%)

 

 II

5 (27.8%)

4 (22.2%)

 

 IIIa

3 (16.7%)

0 (0%)

 

 IIIb

1 (5.6%)

0 (0%)

 

 IV

0 (0%)

4 (22.2%)

 

Gender, n (%)

  

1.000

 Female

3 (16.7%)

3 (16.7%)

 

 Male

6 (33.3%)

6 (33.3%)

 

Mitotic count(< 5/50HPF或 > 10/50HPF), n (%)

  

1.000

 High

7 (38.9%)

7 (38.9%)

 

 Low

2 (11.1%)

2 (11.1%)

 

Tumor site, n (%)

  

0.156

 Mesenterium

0 (0%)

1 (5.6%)

 

 Omentum

0 (0%)

2 (11.1%)

 

 Peritoneum

0 (0%)

1 (5.6%)

 

 Rectum

1 (5.6%)

0 (0%)

 

 Small intestine

3 (16.7%)

0 (0%)

 

 Stomach

5 (27.8%)

5 (27.8%)

 

Age, mean ± SD

53.78 ± 5.74

58.78 ± 8.18

0.153