Transcriptomes of the tumor-adjacent normal tissues are more informative than tumors in predicting recurrence in colorectal cancer patients

Table 1 Patient characteristics

Variable	nonRC, N = 48^a	RC, N = 25^a	Unknown, N = 7^a	P-value^b
Sex				0.4
F	6 (12%)	1 (4.0%)	1 (14%)
M	42 (88%)	24 (96%)	6 (86%)
Age	62 (51, 70)	66 (51, 74)	75 (64, 77)	0.14
TNM stage				0.2
0	1 (2.1%)	0 (0%)	0 (0%)
I	4 (8.3%)	2 (8.0%)	1 (14%)
IIA	19 (40%)	5 (20%)	1 (14%)
IIB	1 (2.1%)	0 (0%)	0 (0%)
IIC	1 (2.1%)	0 (0%)	0 (0%)
IIIA	3 (6.2%)	0 (0%)	0 (0%)
IIIB	17 (35%)	11 (44%)	4 (57%)
IIIC	2 (4.2%)	7 (28%)	1 (14%)
MSI				0.045
MSI-H	9 (19%)	0 (0%)	1 (14%)
MSS	39 (81%)	25 (100%)	6 (86%)

^an(%); Median (IQR)
^bFor dichotomous variables (ex. Sex, MSI), Fisher’s exact test was used, while for variables with more than two groups such as Age, TNM stage, Kruskal–Wallis rank sum test was employed

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