Identification of the MMP family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma

Table 1 The mRNA levels of the MMP family in different types HNSC tissues and normal tissues at transcriptome level

TLR	Type	Fold change	P value	T test	References
MMP1	Oral Cavity Squamous Cell Carcinoma (57)	86.331	5.71E−44	30.373	Peng et al. [20]
MMP3	Tongue Squamous Cell Carcinoma (26)	10.568	1.06E−12	10.471	Ye et al. [21]
ILF3	Tongue Squamous Cell Carcinoma (3)	2.019	4.38E−5	7.408	Kuriakose et al. [22]
MMP7	Head and Neck Squamous Cell Carcinoma4 (41)	7.534	7.00E−14	10.461	Ginos et al. [23]
MMP9	Head and Neck Squamous Cell Carcinoma5 (41)	11.764	7.07E−26	19.530	Ginos et al. [23]
MMP10	Oral Cavity Squamous Cell Carcinoma (57)	25.608	5.49E−32	20.959	Peng et al. [20]
MMP11	Head and Neck Squamous Cell Carcinoma (34)	10.020	3.88E−6	9.649	Cromer et al. [24]
MMP12	Head and Neck Squamous Cell Carcinoma (41)	15.603	5.50–24	17.721	Ginos et al. [23]
MMP13	Head and Neck Squamous Cell Carcinoma (41)	15.206	6.80E−12	8.766	Ginos et al. [23]
MMP16	Thyroid Gland Papillary Carcinoma (14)	2.127	2.26E−4	4.703	Vasko et al. [25]
MMP15	Buccal Mucosa Squamous Cell Carcinoma (2)				Kuriakose et al. [22]
	Floor of Mouth Squamous Cell Carcinoma (1)
	Gingival Squamous Cell Carcinoma (2)
	Glottis Squamous Cell Carcinoma (2)
	Hard Palate Squamous Cell Carcinoma (1)
	Lip Squamous Cell Carcinoma (1)
	Maxillary Sinus Squamous Cell Carcinoma (1)
	Oral Cavity Squamous Cell Carcinoma (2)
	Oropharyngeal Squamous Cell Carcinoma (1)
	Postcricoid Squamous Cell Carcinoma (1)
	Soft Palate Squamous Cell Carcinoma (2)
	Supraglottic Squamous Cell Carcinoma (2)
	Tongue Squamous Cell Carcinoma (3)
	Tonsillar Squamous Cell Carcinoma (1)

ISSN: 1479-5876