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Table 1 Clinical characteristics of patients in prognostic model

From: Immune profiling and prognostic model of pancreatic cancer using quantitative pathology and single-cell RNA sequencing

 

Total

Model 1

High risk

P_value

Model 2

High risk

P_value

Low risk

Low risk

PDAC patients (n)

66

33

33

33

33

Sex (F [%])

35 (53.03)

21 (63.64)

14 (21.21)

0.084

21 (63.64)

14 (21.21)

0.084

Age (years)

63.27 ± 10.21

63.73 ± 9.35

62.82 ± 11.14

0.721

65.30 ± 9.88

61.24 ± 10.28

0.107

Grade (n [%])

 1

9 (13.64)

6 (18.18)

3 (9.09)

0.609

6 (18.18)

3 (9.09)

0.233

 2

21 (31.82)

9 (27.27)

12 (36.36)

 

11 (33.33)

10 (30.30)

 

 3

36 (54.55)

18 (54.55)

18 (54.55)

 

16 (48.48)

20 (60.61)

 

TNM stage (n [%])

 I

28 (42.42)

17 (51.52)

11 (33.33)

0.177

17 (51.52)

11 (33.33)

0.359

 II

16 (24.24)

9 (27.27)

7 (21.21)

 

8 (24.24)

8 (24.24)

 

 III

10 (15.15)

4 (12.12)

6 (18.18)

 

3 (9.09)

7 (21.21)

 

 IV

12 (18.18)

3 (9.09)

9 (27.27)

 

5 (15.15)

7 (21.21)

 

Tumor site (n [%])

 Head

44 (66.67)

20 (60.61)

24 (72.73)

0.296

18 (54.55)

26 (78.79)

0.068

 Body/Tail

22 (33.33)

13 (39.39)

9 (27.27)

 

15 (45.45)

7 (21.21)

 

 CA 19–9 (U/ml)

197.15 (68.59–884.13)

173.20 (44.80–821.15)

199.30 (69.08–1000.00)

0.657

212.20 (48.71–821.15)

195.00 (68.58–944.80)

0.944

 Vascular invasion (n [%])

10 (15.15)

6 (18.18)

4 (12.12)

0.492

5 (15.15)

5 (15.15)

1

 Intravascular cancer embolus (n [%])

21 (31.82)

9 (27.27)

12 (36.36)

0.428

8 (24.24)

13 (39.39)

0.186

 Perineural invasion (n [%])

19 (28.79)

9 (27.27)

10 (30.30)

0.786

9 (27.27)

10 (30.30)

0.786

 Peripancreatic infiltarion (n [%])

48 (72.73)

21 (63.64)

27 (81.82)

0.097

22 (66.67)

26 (78.79)

0.269

 Distant metastasis (n [%])

11 (16.67)

3 (9.09)

8 (24.24)

0.099

4 (12.12)

7 (21.21)

0.322

 Lymph node metastasis (n [%])

26 (39.39)

12 (36.36)

14 (42.42)

0.614

11 (33.33)

15 (45.45)

0.314

 Maximum diameter (cm)

3.5 (3.0–4.5)

3.5 (3.0–4.25)

3.5 (2.25–4.5)

0.746

3.5 (3.0–4.5)

3.5 (2.25–4.25)

0.902