Fig. 7

Immune profiles of PDAC and adjacent noncancerous tissues. A–B t-SNE plot showing renamed T cell subpopulations (A), specimens derived information in PDAC (B). Each dot represented one cell, and cell types were coded with different colors. C–D t-SNE plot showing the T cell subclustering analysis of adjacent noncancerous tissues. E–F Violin plots showing the normalized expression levels of known signature genes of distinct T cell subpopulations. G–H The distribution of PDCD1 + (PD1 +) T cells in PDAC and adjacent noncancerous tissues. The intensity of color (from white to yellow) indicated the average expression level of PDCD1. I–J t-SNE plot showing original cell cluster of macrophages (I), specimens derived information in PDAC (J). Each dot represented one cell, and cell types were coded with different colors. K–L t-SNE plot showing the macrophage subclustering analysis of adjacent noncancerous tissues. (M–N) The distribution of CD2741 + (PD-L1 +) macrophages in PDAC and adjacent noncancerous tissues. The intensity of color (from white to red) indicated the average expression level of CD274