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Table 1 Baseline information of the metabolic syndrome cohort (big cohort)

From: Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism

 

HrEF (n = 190)

HFmrEF (n = 259)

nornal EF (n = 4323)

p value

Age

63.76 ± 10.33

64.03 ± 11.25

63.09 ± 10.67

ns

Sex (Female%)

43.15

42.93

42.06

ns

EF (%)

33.20 ± 5.74

45.76 ± 2.77

67.09 ± 5.94

p < 0.001

LVEDD (mm)

65.56 ± 8.46

57.85 ± 6.19

49.23 ± 4.09

p < 0.001

LVESD (mm)

54.67 ± 8.31

46.05 ± 3.89

30.59 ± 3.96

p < 0.001

UA (umol/L)

402.87 ± 131.12

364.39 ± 123.03

325.08 ± 86.72

p < 0.001

AST (U/L)

30.56 ± 34.23

30.50 ± 34.90

25.42 ± 39.01

ns

ALT (U/L)

33.97 ± 48.55

36.88 ± 37.41

29.65 ± 27.44

ns

Cre (μmol/L)

97.12 ± 112.65

87.58 ± 73.19

66.53 ± 32.30

p < 0.001

Chol (mmol/L)

3.56 ± 0.88

3.60 ± 0.91

3.88 ± 1.10

ns

TG (mmol/L)

3.24 ± 1.15

3.43 ± 1.09

3.54 ± 1.39

ns

HDL-C (mmol/L)

0.93 ± 0.23

0.94 ± 0.21

1.06 ± 0.29

ns

LDL-C (mmol/L)

2.17 ± 0.90

2.17 ± 0.31

2.21 ± 0.87

ns

HbA1C (%)

6.40 ± 1.31

6.50 ± 1.48

6.04 ± 1.10

p < 0.001

  1. EF, ejection fraction; LVEDD, left ventricular end diastolic diameter; LVESD, left ventricular end systolic diameter; UA, uric acid; ALT, alanine transaminase; AST, aspartate transaminase; Cre, creatinine; Chol, cholesterol; TG, triglycerides; HDL-C, high density lipoprotein; LDL-C, high density lipoprotein