Fig. 6

Expression of CCR5 and CCL5/Rantes after ICH and induction of severe peripheral inflammation. A Double immunofluorescence staining images and magnified representative images of the localization of CCR5 (green) in astrocytes (GFAP, red, scale bar = 50 μm), monocytes (MPO, red, scale bar = 50 μm), and microglial cells (IBA-1, red, scale bar = 20 μm). B, C Western blot images and quantitative analysis of the change in CCR5 levels over time in the ipsilateral hemisphere in the ICH + LPS group. D, E Quantitative analysis of the change in CCL5 levels over time in the ipsilateral hemisphere and serum in the ICH + LPS group. F, G Quantitative analysis of CCL5 levels in the ipsilateral hemisphere and serum in the sham, LPS, LPS + sham, ICH, and ICH + LPS groups 3 days after ICH. The data are expressed as the mean ± SD. ^* vs. the ICH group at 1 day, P < 0.05; ^# vs. the sham group, P < 0.05; ^a vs. the LPS group, P < 0.05; ^b vs. the LPS + sham group, P < 0.05; ^& vs. the ICH group, P < 0.05; ns: no significance