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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: miRNA-seq identification and clinical validation of CD138+ and circulating miR-25 in treatment response of multiple myeloma

Fig. 5

CD138+ overexpression of miR-25 independently predicts MM post-treatment outcome. Forest plots of the univariate A, C and multivariate B, D Cox proportional regression analyses. Multivariate analysis adjusted for CD138+ miR-25 levels, R-ISS stage, high-risk cytogenetics [t(4;14) del (17p13), t(14;16), t(11;14), del(13q)], B2M, LDH and creatinine levels, gender, age, HDM/ASCT and response to 1st line therapy. Internal validation was performed by bootstrap analysis based on 1000 bootstrap samples. HR: Hazard Ratio, 95% CI: 95% confidence interval of the estimated HR

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Journal of Translational Medicine

ISSN: 1479-5876

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