Fig. 2From: Identification of hub genes and potential molecular mechanisms related to radiotherapy sensitivity in rectal cancer based on multiple datasetsRandom survival forest analysis of DEGs in TCGA-READ cohort. A Random survival forest analysis of DEGs. B Eight genes were identified as finial markers with variable relative importance > 0.3. C High expression of PLAGL2, ZNF337 D and ALG10 E were significantly associated with better overall survival compared to low expression by Kaplan-Meier survival analysis (P = 0.018, P < 0.001 and P = 0.007, respectively). F. The expression of ZNF337, PLAGL2 and ALG10 was significant higher in radiotherapy responder READ patients than non-responder patients (* represented P < 0.05)Back to article page