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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury

Fig. 5

mTOR regulates TREM-1-induced mitochondrial fission in macrophages. A–C Protein levels of p-mTORser2448 and p-4E-BP1S65, n = 3. D-E, mitochondrial morphology was stained with TOM20 (green) and the morphological skeleton. F, quantification of mitochondrial morphology, n = 3. G, H Mitochondrial fission-related proteins: TOM20, DRP1Ser616, MTFP1, and PGAM5 proteins, n = 3. G, H Mitophagy-related proteins: Pink1 and Beclin1, n = 3

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