Fig. 5

CircDNAJC11 promotes proliferation and regulates apoptosis of BC cells in vivo. A Representative figures of nude mice in each group (n = 5). B Representative bioluminescence images of the subcutaneous tumor model of nude mice in each group. C Comparison of the tumor weight in each group (n = 5). D Tumor xenograft growth curves for nude mice in each group were measured weekly (n = 5). E Kaplan–Meier survival curves for tumor-bearing mice inoculated with indicated stable MCF-7 cells (n = 10). F Immunohistochemistry for the examination of the expression levels of Ki67, MAPK6, and Caspase-7 in xenograft tumors. Scale bar, 100 μm. Data were presented as mean ± SD in C and D. C and D were analyzed with Student’s t-test, and E was analyzed with the log-rank test. * P < 0.05, ** P < 0.01, ***P < 0.001